GreatSmiles

How Long After Extraction Can You Smoke?

Reviewed 2 September 2026. Twenty-six records, each pulled and re-checked against Europe PMC before publication: three systematic reviews and one meta-analysis of clinical trials, one umbrella review of 69 systematic reviews, three scoping reviews, five cross-sectional or register studies, one case series and several narrative reviews, plus the implant-risk synthesis and two animal studies used only where the article says so. Every number below is printed in the abstract of the record cited beside it. This article exists because the advice patients actually receive is a round number, and the trials that exist do not contain that number. Not medical advice; the questions to ask your own clinician are in the plan section.

The short answers

What a cigarette does to a healing socket

Four separable mechanisms explain why clinicians bother, and why the advice is not only about the suction.

Vasoconstriction. Nicotine is a systemic vasoconstrictor, so the microcirculation feeding the clot and the newly forming granulation tissue is narrowed; the implant literature treats this as the operative pathway and concludes smoking is not an absolute contraindication but has a detrimental effect on peri-implant tissues, with a systematic review of 45 articles (44 studies, follow-up 1 to 17 years) finding a significantly reduced survival in cigarette smokers at both implant and patient level (OR 0.40, 95% CI 0.27 to 0.61) (Elena et al., Clin Oral Implants Res 2026-03-01, PMID 41776304). Oxygen delivery. Smoke raises carboxyhaemoglobin and, in the comparative study of young men who smoked cigarettes or hookah, both groups showed significantly increased red cell count, haemoglobin and haematocrit — the haematological signature of chronic hypoxic stress — alongside an oral bacterial load of 5.96 ± 0.19 log₁₀ CFU/mL in cigarette smokers against 3.70 ± 0.10 in non-smokers (Alghofaili et al., FASEB Bioadv 2026-06-01, PMID 42266505). Cellular toxicity. Beyond nicotine, the aerosol’s flavour aldehydes produced oxidative injury, IL-8 and PGE2 release and apoptosis in oral fibroblasts, the cells that rebuild the wound matrix (Kang et al., Anat Cell Biol 2026-06-01, PMID 42124527). Saliva. Vaping is associated with lower flow, lower buffering capacity and lower pH (Alsenani et al., BMC Oral Health 2025-11-01, PMID 41261418) — the fluid that clears bacteria and buffers acid after a clot is gone.

Read together, this is why “it was only one puff” is the wrong frame: the risk is not a mechanical lottery in which you either dislodge the clot or you do not, it is a dose-dependent reduction in the perfusion and cellular machinery the socket needs, beginning within minutes of the first exposure.

Added risk of wound complications in active smokersFold increase over non-smokers reported across studies of facial procedures; bar length is the same scaleLowest reported in the review1.8 xHighest reported in the review12.0 x112fold increase in risk
Source: Chouksey G, Agrawal A, Bhargava S, Karna ST, Archives of Craniofacial Surgery 2026;27(1):1-9, PMID 41787902 — a scoping review in which nine of 129 screened records met the inclusion criteria, and active smoking was consistently associated with impaired wound healing after facial procedures, with reported complication risks between 1.8-fold and 12-fold higher than in non-smokers. One source, one unit (fold increase in risk). These are craniofacial and reconstructive outcomes, not extraction outcomes: the bars show why the direction of the effect is not in dispute, and because the review did not pool its results, the spread is reproduced exactly as published.

Vaping, heated tobacco and hookah: what is actually known

The device-specific evidence in the mouth is thin but not empty, and the honest summary is that vaping looks less harmful than burning while still being measurably different from not using anything.

Nicotine pouches, snus and the “at least it’s not smoke” argument

Patients increasingly ask about pouches because they can be used where smoking cannot. Two findings should be read together. First, pouches are not tissue-neutral: in a cross-sectional study of 126 nicotine-pouch users, 63 users of tobacco-derived pouches and 83 non-users, oral lesions were found in 79% of nicotine-pouch users and 89% of tobacco-pouch users, with erythema and symptoms more frequent in the nicotine-pouch group and hyperkeratosis predominating in the tobacco group, and a non-significant trend toward worse lesions with mint flavouring; no increased caries or periodontal risk was seen with up to six years of use (Daneshian et al., Oral Dis 2026-07-01, PMID 42384425). A systematic review of Swedish smokeless tobacco (26 studies of 2 176) found associations with gingival recession, especially with loose snus, more gingivitis independent of plaque, no significant association with periodontitis, inconsistent caries findings, plus tooth wear and self-reported temporomandibular symptoms — and a 48% higher risk of oral cleft malformations in offspring of mothers using snus in pregnancy (Bankvall et al., Acta Odontol Scand 2026-02-01, PMID 41649495).

Second, the harm-reduction case is real but unfinished: pouches show significantly lower harmful-constituent levels than cigarettes and traditional smokeless tobacco, and short-term clinical studies report reduced mucosal irritation and gingival inflammation in exclusive users, but no long-term epidemiological evidence exists on oral carcinogenesis and the available human studies are few, small and heterogeneous (La Rosa et al., Front Oral Health 2026-01-01, PMID 41737135). Where the socket is concerned, the relevant question is not carcinogenicity but perfusion and bone biology — and there the animal and in vitro synthesis shows nicotine itself slowing bone healing in a dose-dependent way, with the caveat that human isolation studies do not exist (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042). Placing a pouch against the gum next to a fresh extraction is the worst version of this option: it delivers the vasoconstrictor locally, at high concentration, onto a wound.

Cannabis: the anaesthesia problem nobody screens for

The dental literature on cannabis is small and mostly non-experimental, which is exactly why it should be read carefully rather than quoted either way. A systematic review of cannabinoid drugs and oral health reviewed the receptors in oropharyngeal tissue and the putative associations with oral disease, and argued for recording cannabis use in the dental record as a matter of good practice (Bellocchio et al., Int J Mol Sci 2021-08-01, PMID 34361095). For pain, the review of five studies found one positive result (topical cannabidiol in temporomandibular disorder) against four nulls, concluding that evidence is insufficient for a tangible clinical benefit (Votrubec et al., Aust Dent J 2022-12-01, PMID 36082517); a later systematic review found four randomised trials, three at low risk of bias, and nine animal studies, all at high risk of bias, with CBD sometimes reducing dental or myofascial pain and sometimes no better than NSAIDs or corticosteroids (Campana et al., Int J Mol Sci 2025-04-01, PMID 40332414).

The practical, extraction-specific signal is the anaesthesia and hyperalgesia report: chronic use was associated with difficulty achieving adequate block and an amplified pain response during extraction, and the authors’ recommendation is that clinicians ask about cannabis when planning anaesthesia and adapt the technique rather than treat it as noise (Hammoud et al., Toxicol Rep 2026-12-01, PMID 42404491). If you are a regular user, the useful action is therefore not deciding whether to use before the appointment — it is telling the operator beforehand, because dosing, technique and the post-operative analgesic plan can all be adjusted in advance, and a failed block in a chair with a swelling face is a long afternoon (Hammoud et al., Toxicol Rep 2026-12-01, PMID 42404491) (Kumar et al., Int Dent J 2026-06-01, PMID 41932095).

The numbers borrowed from other operations, and their limits

Dentistry has few trials of smoking timing, so clinicians reason from surgical fields that do. A scoping review of wound healing after facial procedures found nine of 129 screened studies met criteria, and active smoking was consistently associated with impaired healing with complication risks reported between 1.8-fold and 12-fold higher (Chouksey et al., Arch Craniofac Surg 2026-02-01, PMID 41787902). The largest single dataset here is a propensity-matched network analysis: 56,992 breast-reconstruction cases paired into two cohorts of 28,496, where documented nicotine dependence within six months before surgery raised seroma (RR 1.224, 95% CI 1.177 to 1.274) and also capsular contracture and implant-related mechanical complications, while lymphedema and flap loss did not differ significantly (Tanas et al., Plast Reconstr Surg Glob Open 2026-05-01, PMID 42145836). A systematic review of 62 studies on non-tobacco nicotine and bone healing supplies the mechanism, and the same authors flag the gap: no human studies isolate nicotine from smoke or aerosol (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042).

Say plainly what these are and are not. They are not extraction studies. A jaw socket is not a breast pocket, and the risk multipliers cannot be quoted to a patient as if they measured dry socket. What they do establish is that the direction and the size of the effect on wound healing are not marginal in any surgical field measured, which is why dentists treat this as worth an instruction rather than a shrug (Chouksey et al., Arch Craniofac Surg 2026-02-01, PMID 41787902) (Tanas et al., Plast Reconstr Surg Glob Open 2026-05-01, PMID 42145836).

What measurably reduces the risk

How to read this like a clinician

Evidence at a glance

Question Estimate as printed Design and caveat
Does smoking raise post-extraction complications? Overall complication rate 11.0%; alveolar osteitis 3.4%; persistent pain 4.1%; smoking, uncontrolled diabetes and hypertension the significant patient factors Retrospective audit, tertiary dental hospital, consecutive extractions (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643)
Is 48 hours evidence-based? No comparison of abstinence windows exists in the records verified here; the timing guidance is extrapolated from risk data and mechanism Stated as an absence, not a null result (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643) (Chouksey et al., Arch Craniofac Surg 2026-02-01, PMID 41787902)
Does gauze over the socket make it safe? Not tested. Documented mechanisms (vasoconstriction, oxygen delivery, fibroblast toxicity, salivary change) are not mechanical In vitro and cross-sectional mechanism evidence (Kang et al., Anat Cell Biol 2026-06-01, PMID 42124527) (Alsenani et al., BMC Oral Health 2025-11-01, PMID 41261418)
Vaping and the mouth All vapers had low resting saliva; low buffering 36.8% vs 1.2%; acidic pH 92.9% vs 7.1%; oral bacterial load 5.96 vs 3.70 log₁₀ CFU/mL in cigarette smokers vs non-smokers Pilot cross-sectional (20 vs 19); comparative cross-sectional (87 men) (Alsenani et al., BMC Oral Health 2025-11-01, PMID 41261418) (Alghofaili et al., FASEB Bioadv 2026-06-01, PMID 42266505)
Vaping and periodontium Smokers worse than vapers and non-smokers on GI, PI, PD > 3 mm and CAL; e-cigarette users show worsened periodontal status and poorer treatment response in some studies; microbiota distinct with Veillonella, Leptotrichia, Fusobacterium SR of 13 studies; narrative review; SR of 12 microbiota studies with very low certainty (Aldalaeen et al., Health Sci Rep 2025-09-01, PMID 40959186) (Robson et al., Br Dent J 2025-11-01, PMID 41315696) (La Rosa et al., J Clin Periodontol 2026-06-01, PMID 41856754)
Nicotine pouches and snus Oral lesions in 79% of pouch users and 89% of tobacco-pouch users vs non-users; snus: gingival recession, more gingivitis, no periodontitis association, +48% oral clefts with maternal use Cross-sectional (272 participants); SR of 26 studies (Daneshian et al., Oral Dis 2026-07-01, PMID 42384425) (Bankvall et al., Acta Odontol Scand 2026-02-01, PMID 41649495)
Non-tobacco nicotine and bone Dose-dependent inhibition of osteoblast proliferation, delayed healing, slowed osseointegration; anti-inflammatory at low doses; no human isolation studies SR of 62 mostly animal and in vitro studies (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042)
Cannabis and anaesthesia Hyperalgesia and inadequate block in a chronic user at extraction; for pain, one positive trial of topical CBD in TMD against four nulls; 4 RCTs (3 low RoB) and 9 animal studies (all high RoB) Case report plus two systematic reviews (Hammoud et al., Toxicol Rep 2026-12-01, PMID 42404491) (Votrubec et al., Aust Dent J 2022-12-01, PMID 36082517) (Campana et al., Int J Mol Sci 2025-04-01, PMID 40332414)
What reduces the risk Chlorhexidine 9.58% vs 16.8%; PRF RR 0.33 (0.20 to 0.53, 776 sites); rofecoxib OR 1.89 (1.15 to 3.10); phone follow-up adherence 9.7 vs 7.9 Meta-analysis of 12 studies; SR of 7 RCTs; SR/MA of 32 trials; SR of 10 instruction studies (Bucataru et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41273739) (Ávila-Oliver et al., Med Oral Patol Oral Cir Bucal 2025-05-01, PMID 40121674) (Isiordia-Espinoza et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41578912) (Fawzy et al., Clin Cosmet Investig Dent 2026-01-01, PMID 42222518)
Implants and smoking Implant survival OR 0.40 (95% CI 0.27 to 0.61) in smokers, follow-up 1 to 17 years; counselling recommended rather than exclusion SR of 45 articles (44 studies) (Elena et al., Clin Oral Implants Res 2026-03-01, PMID 41776304)
Whole-body vaping risk Heart rate MD 1.41 (0.81 to 2.01; I² = 91%); SBP MD 0.51 (0.26 to 0.75); asthma OR 1.30 (1.1 to 1.55) Umbrella review of 69 SRs (Kaur et al., BMJ Open 2025-10-01, PMID 41073111)
Secondhand smoke and children’s teeth In a 672-child survey, passive smoking was associated with higher dft (p = 0.021) unadjusted but not after adjustment; in rats, secondhand exposure widened enamel prism spacing and lowered molar phosphorus (p = 0.033) Cross-sectional with confounding by socioeconomic factors; animal study (Lam et al., J Dent 2025-10-01, PMID 40639604) (de Lima Gonçalves et al., Calcif Tissue Int 2026-05-01, PMID 42101651)

What the evidence does not support

Cost, coverage and the Utah part

Utah’s published children’s dental benefit summary contains no line for tobacco or nicotine products, no cessation-counselling benefit and no implant line: the words do not appear in the document, which instead sets out the surgical rules that matter in the days after an extraction. Simple extractions are covered without prior authorisation and the benefit text notes the service includes routine removal, the numbing of the area and any necessary stitches; surgical extractions, defined as cases needing bone removal or tooth sectioning, likewise require no prior authorisation; both are covered when a tooth cannot be saved by a filling or a root canal; wisdom tooth removal is covered only when the teeth are impacted or causing pain; emergency treatment of an abscess or acute infection (exam, diagnostic x-rays, incision and drainage) requires no authorisation; and inpatient hospital costs are billed to the medical plan, while general anaesthesia and intravenous sedation are covered only where a child cannot be treated safely under local anaesthesia because of disability or another complex medical condition, with documentation. Nitrous oxide analgesia is explicitly a non-covered service (data as of 4 February 2026; see Additional documents).

Practically, three consequences follow for a family. A complication that could have been avoided by the instruction is still paid for as an emergency visit, so the cheap insurance is the timing rule, not the prescription. If a socket infection develops, it is covered at the urgent-care level without paperwork, but the sequelae of repeated complications — the second extraction, the graft, the eventual implant — are not the same conversation: the children’s benefit lists partial dentures one upper and one lower every five years with prior authorisation and generally excludes fixed bridges, and nothing about implants at all. And where sedation is the plan for an anxious adolescent, note that the route Medicaid funds is intramuscular or intraoral injection or, for complex medical cases, monitored anaesthesia in a hospital — the in-chair laughing-gas option that many clinics advertise is not funded, which is worth knowing before it is offered as the default (data as of 4 February 2026).

A plan for the first 72 hours, and days 4 to 7

Frequently asked questions

Can I smoke 24 hours after extraction? The best verified answer is that at 24 hours the tissue is at its most vulnerable and the audit finds smoking among the significant risk factors for exactly the complications that appear on days 2 to 4; nobody has tested 24 hours as a safe point (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643) (Isiordia-Espinoza et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41578912).

Can I smoke 5 days after extraction, or after the stitches? Day 5 is past the highest-risk window for clot loss, but granulation and early bone organisation are still running, and the animal and in vitro bone data are the reason the recommendation is not “fine on day 5” but “later and less is better, and the first three days matter most” (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042) (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643).

What if I already smoked? Nothing resets to zero and nothing is doomed: stop now, keep the rinse, avoid the socket with any device, do not start selective COX-2 cover, and call if pain escalates on day 2 or 3 (Bucataru et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41273739) (Isiordia-Espinoza et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41578912) (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643).

Is vaping safer than smoking after extraction? On the periodontal and systemic evidence, likely less harmful than burning; on mouth-specific healing it is still associated with low flow, low buffering, acidity, distinct microbiota and in young people with lesions — and no socket trial exists for either product, so the answer for the wound is: neither is neutral (Aldalaeen et al., Health Sci Rep 2025-09-01, PMID 40959186) (Alsenani et al., BMC Oral Health 2025-11-01, PMID 41261418) (La Rosa et al., J Clin Periodontol 2026-06-01, PMID 41856754) (Tran et al., Int J Paediatr Dent 2026-07-01, PMID 41992606).

Can I use a nicotine pouch instead? Away from the surgical site, it removes smoke, heat and carbon monoxide from the wound, and the reviews treat pouches as lower-toxicant products than cigarettes (La Rosa et al., Front Oral Health 2026-01-01, PMID 41737135). It does not remove nicotine, which is the substance with dose-dependent bone and fibroblast findings and the reason the peri-operative period is exactly when the “less nicotine” version of the advice matters (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042) (Kang et al., Anat Cell Biol 2026-06-01, PMID 42124527).

Does hookah or heated tobacco count? Yes. Hookah users in the comparative study showed disrupted oral microbiota and raised red-cell indices alongside cigarette smokers, and heated products still deliver nicotine and aerosol chemistry to the same mucosa (Alghofaili et al., FASEB Bioadv 2026-06-01, PMID 42266505) (La Rosa et al., J Clin Periodontol 2026-06-01, PMID 41856754).

I only smoke cannabis. Does the rule apply? The inhalation part applies to the wound as much as any smoke, and the specific cannabis issue for your appointment is anaesthesia: the case literature reports inadequate block and increased pain response, so disclosure before the procedure is the single most useful thing you can do (Hammoud et al., Toxicol Rep 2026-12-01, PMID 42404491) (Bellocchio et al., Int J Mol Sci 2021-08-01, PMID 34361095).

Is secondhand smoke a dental problem for my kids? The child data are honest about their limits: in 672 preschoolers, exposure was associated with higher decay scores before adjustment and not after, and the enamel effects in secondhand-smoke-exposed rats (wider prism spacing, lower molar phosphorus) are animal findings (Lam et al., J Dent 2025-10-01, PMID 40639604) (de Lima Gonçalves et al., Calcif Tissue Int 2026-05-01, PMID 42101651). Household smoke reduction is worth doing on many grounds; as a caries intervention in itself it is unproven.

I’m having an implant. Must I stop completely? The synthesis says: not an absolute contraindication, but a measured survival penalty (OR 0.40, 95% CI 0.27 to 0.61) with cessation counselling recommended inside the treatment plan rather than as a precondition (Elena et al., Clin Oral Implants Res 2026-03-01, PMID 41776304).

Glossary: kitchen words ↔ chart words

What you say at home What is in the notes How studies measure it
“can I smoke yet” Peri-operative nicotine and smoke exposure after extraction Complication prevalence and risk-factor regression in extraction audits (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643)
“dry socket” Alveolar osteitis; clot loss with exposed bone, days 2 to 4 Incidence per site; pooled against chlorhexidine and PRF (Bucataru et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41273739) (Ávila-Oliver et al., Med Oral Patol Oral Cir Bucal 2025-05-01, PMID 40121674)
“I covered it with gauze” Mechanical barrier; no effect on vasoconstriction or oxygen carriage Not represented in any verified trial; mechanism studies are in vitro (Kang et al., Anat Cell Biol 2026-06-01, PMID 42124527)
“I just vape” Electronic nicotine delivery system use Salivary flow, pH and buffering; microbiota community structure; periodontal indices (Alsenani et al., BMC Oral Health 2025-11-01, PMID 41261418) (La Rosa et al., J Clin Periodontol 2026-06-01, PMID 41856754) (Aldalaeen et al., Health Sci Rep 2025-09-01, PMID 40959186)
“pouch in the lip” Tobacco-free nicotine pouch; mucosal lesion, erythema Graded mucosal examination in cross-sectional comparison (Daneshian et al., Oral Dis 2026-07-01, PMID 42384425)
“snus is harmless” Smokeless tobacco; recession, gingivitis, pregnancy cleft risk Systematic review of 26 studies (Bankvall et al., Acta Odontol Scand 2026-02-01, PMID 41649495)
“weed before I go under” Chronic cannabinoid exposure; hyperalgesia, block failure Case report and systematic reviews of pain trials (Hammoud et al., Toxicol Rep 2026-12-01, PMID 42404491) (Votrubec et al., Aust Dent J 2022-12-01, PMID 36082517)
“the strong painkillers for wisdom teeth” Selective COX-2 inhibitor analgesia Meta-analysis with alveolar osteitis as an adverse outcome (Isiordia-Espinoza et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41578912)
“will the implant fail” Peri-implant bone and soft-tissue healing in smokers Survival odds ratio with follow-up to 17 years (Elena et al., Clin Oral Implants Res 2026-03-01, PMID 41776304)
“the rinse they gave me” Chlorhexidine mouth rinse, local antiseptic protocol Pooled relative reduction versus control in third-molar surgery (Bucataru et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41273739)

Related reading on this site: what to do about a toothache at night, what to eat and drink in the first days, which swelling signs mean the emergency department and what the peroxide evidence says about whitening.

How this page was built, and what it cannot tell you

Method: candidate records were located in Europe PMC with queries that mirror real searches (“how long to not smoke after extraction”, “can i vape after tooth extraction”, “nicotine pouches after tooth extraction”, “чи можна курити після видалення зуба”, “cuándo puedo fumar después de una extracción”), and every record used — authors, journal, volume, pages, DOI, PMID, open-access flag, citation count — was re-fetched on the day of publication and is reproduced below with its DOI. Numbers come from the retrieved abstracts; intervals are reproduced as printed; where the abstract is a case report or an animal study, the article says so rather than upgrading it. The figure uses one source reporting one unit. Coverage statements were read from the CMS InsureKidsNow benefit summary for Utah Medicaid (data as of 4 February 2026) and checked against that text, including the negative findings: no cessation-counselling and no implant line exist in that document. The central limitation is structural: this topic is dominated by audits, cross-sectional designs, in vitro work and borrowed surgical data, and the one number patients most want — how many hours — is not in any of it (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643) (Chouksey et al., Arch Craniofac Surg 2026-02-01, PMID 41787902) (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042).

What this page cannot tell you: your personal risk, because the verified evidence does not model dose-times-day-since-surgery interaction, and the audit reports group-level association, not individual prediction (Dignam et al., Aust Dent J 2025-12-01, PMID 40492643). It cannot tell you a safe single cigarette, a safe puff, or a safe day, and it cannot tell you whether pouches delay bone healing in humans, because the isolation studies do not exist (Travis et al., J Orthop Surg Res 2026-03-01, PMID 41782042). What it can do is keep the advice in proportion: the earliest days matter most, inhaled and locally placed nicotine are the modifiable parts, chlorhexidine and PRF and a phone call are the parts with numbers behind them, and disclosure about cannabis changes the anaesthetic plan rather than your eligibility (Bucataru et al., Med Oral Patol Oral Cir Bucal 2026-05-01, PMID 41273739) (Ávila-Oliver et al., Med Oral Patol Oral Cir Bucal 2025-05-01, PMID 40121674) (Fawzy et al., Clin Cosmet Investig Dent 2026-01-01, PMID 42222518) (Hammoud et al., Toxicol Rep 2026-12-01, PMID 42404491).

Sources

Peer-reviewed evidence

Additional documents

Bibliographic records above were retrieved and verified programmatically from Europe PMC (authors, journal, volume, pages, DOI, PMID, citation count). Coverage, guideline and regulatory statements are quoted from the cited public documents with their dates; verify against the current version before relying on them. This article is not medical or dental advice.

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